At Linde, we provide critical gases and cryogens that sustain daily operations for our pharmaceutical and biotechnology customers. From research and development through scale-up and into full production, we have the gases you need, the way you need them. And Linde’s experience goes well beyond gas supply. Our advanced application expertise in gas-liquid mixing and temperature control engineering can help you achieve the process reproducibility, drug uniformity, product quality and cost savings you need to make the world a healthier place. So whether you’re tasked with drug discovery, process development, manufacturing, quality control, cell preservation, or any other facet of the industry, Linde’s broad gas portfolio (GMP and non-GMP), application innovation and supply distribution will help control the process, so you can focus on finding the cure.
Gaseous nitrogen is commonly used for blanketing — protecting a process from moisture intrusion, oxidation, degradation and contamination. Additional uses include purging, pressure transferring, mixing and capturing air emissions. Cryogenic liquid nitrogen is used to control the temperature in reactor cooling applications and to preserve biological samples.
Carbon dioxide is used throughout the pharmaceutical market. As a gas, it is used in bench top incubators. In manufacturing, it is used in super critical fluid chromatography. And in wastewater treatment, it is used for self-buffered pH control.
Linde’s advances in liquid-nitrogen-based lyophilization technology have provided customers with greater operational flexibility, improved reliability and fewer maintenance demands. Our patented NCOOL™ heat exchanger has a refrigeration efficiency of > 95% and uses significantly less nitrogen than alternative cryogenic refrigeration systems. With high turn down capability, a compact footprint, and environmentally friendly operation, Linde’s NCOOL technology is ideal for today’s demanding lyophilization requirements.
Linde’s cryogenic VOC (Volatile Organic Compounds) Recovery systems allow customers to comply with stringent emission regulations. We’ll work with you to fully understand your process, company-specific environmental initiatives, and regulatory restrictions. In turn, we’ll help you develop a comprehensive VOC recovery plan to meet your needs and your budget.
At Linde, we offer a wide range of cryogenic storage equipment, including cryogenic freezers, controlled rate freezers and refrigeration back-up, critical for maintaining and handling biological materials.
Linde has a complete repository offering including cryogenic storage freezers, cryoshippers, controlled rate freezers and O2 monitors. We also design and build CO2 back up systems for -80C° freezers, changeover panels, and a variety of gas handling equipment. As a fully integrated supplier, Linde provides cryogenic liquid nitrogen in dewars, microbulk and bulk tanks.